3 unstoppable ASX shares to buy and hold for the next decade

These shares are going places over the remainder of the decade and beyond.

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When it comes to building long-term wealth in the share market, few strategies are as powerful as identifying quality ASX shares and simply holding them for the long haul.

While markets rise and fall, great companies tend to keep growing over time — rewarding patient investors handsomely.

With that in mind, here are three unstoppable ASX shares that could have the potential to deliver outstanding returns over the next decade.

Goodman Group (ASX: GMG)

The first ASX share to buy and hold could be Goodman. It is a global leader in industrial property, developing and managing logistics warehouses, data centres, and last-mile distribution facilities.

Goodman has made a name for itself by partnering with some of the biggest names in e-commerce and cloud computing, including Amazon and Microsoft. As demand for logistics and digital infrastructure continues to rise, Goodman's development pipeline and global footprint put it in an enviable position.

It is also betting big on data centres, which are in demand due to the cloud computing and artificial intelligence megatrends. Overall, it is riding powerful secular tailwinds that make it a long-term standout.

Pro Medicus Ltd (ASX: PME)

Another unstoppable ASX share that could be a buy is Pro Medicus. It has quietly become one of Australia's most successful tech exports. The company develops high-performance medical imaging software used by some of the world's top hospitals and research institutions.

Its flagship product, Visage, helps radiologists read images faster and more accurately, and demand continues to grow as healthcare systems modernise. Importantly, Pro Medicus operates on a highly scalable, software-as-a-service (SaaS) model with exceptional profit margins.

With a robust sales pipeline, long-term partnerships, and the increasing importance of AI-driven diagnostics, Pro Medicus is in a sweet spot to continue compounding its earnings well into the future.

Xero Ltd (ASX: XRO)

Finally, Xero could be an ASX share to buy for the long term. It has transformed from a New Zealand startup into a global leader in cloud accounting software. Its intuitive platform is used by 4.4 million small businesses and accountants across the globe.

What makes Xero so compelling is the sticky nature of its business. Once a small business is integrated into Xero's ecosystem, they are unlikely to leave. That recurring revenue model, combined with ongoing international expansion, especially in the US and UK, positions Xero for sustained growth in a market estimated to be 100 million small to medium sized businesses.

Over the next decade, as more businesses move away from legacy software and embrace digital solutions, Xero stands to be one of the biggest beneficiaries.

John Mackey, former CEO of Whole Foods Market, an Amazon subsidiary, is a member of The Motley Fool’s board of directors. Motley Fool contributor James Mickleboro has positions in Goodman Group, Pro Medicus, and Xero. The Motley Fool Australia's parent company Motley Fool Holdings Inc. has positions in and has recommended Amazon, Goodman Group, Microsoft, and Xero. The Motley Fool Australia's parent company Motley Fool Holdings Inc. has recommended Pro Medicus and has recommended the following options: long January 2026 $395 calls on Microsoft and short January 2026 $405 calls on Microsoft. The Motley Fool Australia has positions in and has recommended Xero. The Motley Fool Australia has recommended Amazon, Goodman Group, Microsoft, and Pro Medicus. The Motley Fool has a disclosure policy. This article contains general investment advice only (under AFSL 400691). Authorised by Scott Phillips.

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